Glioblastoma (GBM)-derived tumorigenic stem-like cells (GSCs) may play a key role in therapy resistance.Previously, we reported that the mitotic kinase MELK binds and phosphorylates the oncogenic transcription factor FOXM1 in GSCs.Here, we demonstrate that the catalytic subunit of Polycomb repressive complex 2, EZH2, is targeted by the MELK-FOXM1 c
People with strong (vs.moderate) political attitudes have been shown to exhibit less phasic reactivity to perceptual Platinum Edition anomalies, presumably to prevent their committed meaning systems from being challenged by novel experiences.Several researchers have proposed that (but not tested whether) firmly committed individuals also engage in
Footprint 19 focuses on the more recent roles of architecture in the contemporary spaces of conflict.Departing from a spatial understanding of geopolitical, Girls Easter Top climatological and economical conflicts, the various contributions highlight the large scale and phenomenal transitions in the physical world and in society by extrapolating, t
Introduction.Exaggerated placental site reaction is a rare benign non-neoplastic lesion and presents with infiltration of the endometrium and myometrium by intermediate trophoblastic cells at the implantation site.This reaction may occur 76% MACA CHOC BAR following healthy or ectopic pregnancy, aborts, or molar pregnancy.The diagnosis is only histo
Bioluminescence is ubiquitous in marine ecosystems and found in uni- and multicellular organisms.Bioluminescent displays can be used to deter predators, attract mates, and lure and hunt prey.Mechanically stimulated flash kinetics of zooplankton and dinoflagellates are life stage-dependent and species-specific, and could prove effective at identific